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TPS5604 : TRIOC: A randomised parallel group double-blind phase II study to assess the activity of MVA-5T4 vaccine versus placebo in patients with relapsed asymptomatic epithelial ovarian, fallopian tube, or primary peritoneal cancer.

Researchers

Presenter

  • Agnieszka Michael

Principal Investigators

  • Rosemary Lord

  • Geoff Hall

  • Louise Hanna

  • Anjana Anand

  • Axel Walther

  • Shibani Nicum

  • Andrew R. Clamp

  • Rebecca Sophie Kristeleit

  • Alan Hackshaw

  • Gita Parmar

  • Yen Ngai

  • Laura Farrelly

  • Sharadah Essapen

  • Iain A. McNeish

  • Richard Harrop

  • Jonathan A. Ledermann

Medical Centers

  • University of Surrey, Guildford, United Kingdom

  • The Clatterbridge Cancer Centre, Liverpool and Wirral, United Kingdom

  • St. James's University Hospital, Leeds, United Kingdom

  • Velindre Cancer Centre, Cardiff, United Kingdom

  • City Hospital Nottingham UK, Nottingham, United Kingdom

  • University of Bristol, Bristol, United Kingdom

  • Oxford University Hospitals NHS Trust, Oxford, United Kingdom

  • The Christie Hospital, Manchester, United Kingdom

  • University College London Hospitals/UCL Cancer Institute, London, United Kingdom

  • Cancer Research UK & UCL Cancer Trials Centre, London, United Kingdom

  • Cancer Research UK & UCL Cancer Trials Centre, London, United Kingdom

  • Cancer Research UK and UCL Cancer Trials Centre/UCL Cancer Institute, London, United Kingdom

  • Medical Research Council Clinical Trials Unit at University College London, London, United Kingdom

  • St. Luke's Cancer Centre, Guildford, United Kingdom

  • Oxford BioMedica, Oxfordshire, United Kingdom

  • Kings College London, London, United Kingdom

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Genetic Disorder

Disease

  • Peritoneal cancer

  • Gynaecological cancer

Biomarkers

  • Carbohydrate antigen 125

Drug/Treatment

  • MVA-5T4

Outcome

  • N/A


Study Design

  • Randomized

  • Placebo Control

  • Double Blind/Blinded

  • Multicenteric

  • Controlled

  • Parallel Group

Phase

  • II

Study Id's

  • NCT01556841

Sponsors

  • N/A

Result

  • N/A