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LBA3 : A phase III randomized clinical trial (RCT) of tandem myeloablative autologous stem cell transplant (ASCT) using peripheral blood stem cell (PBSC) as consolidation therapy for high-risk neuroblastoma (HR-NB): A Children's Oncology Group (COG) study.

Researchers

Presenter

  • Julie R. Park

Principal Investigators

  • Susan G. Kreissman

  • Wendy B. London

  • Arlene Naranjo

  • Susan Lerner Cohn

  • Michael D. Hogarty

  • Sheena Cretella Tenney

  • Daphne Haas-Kogan

  • Peter John Shaw

  • James Duncan Geiger

  • John J Doski

  • Sandra Wooton Gorges

  • Geetika Khanna

  • Stephan D. Voss

  • John M. Maris

  • Stephan A. Grupp

  • Lisa Diller

Medical Centers

  • Seattle Children's Hospital and University of Washington School of Medicine, Seattle, WA

  • Duke University Medical Center, Durham, NC

  • Dana-Farber Cancer Institute, Children's Hospital, Boston, MA

  • Children's Oncology Group Statistics and Data Center, University of Florida, Gainesville, FL

  • The University of Chicago Medical Center, Chicago, IL

  • Childrens Hospital of Philadelphia, Philadelphia, PA

  • Children's Oncology Group Statistics and Data Center, Gainesville, FL

  • Dana-Farber/Harvard Cancer Center, Boston, MA

  • The Children's Hospital at Westmead, Westmead, Australia

  • C S Mott Children's Hospital, Ann Arbor, MI

  • University of Texas Health Science Center San Antonio, San Antonio, TX

  • University of California, Davis Comprehensive Cancer Center, Sacramento, CA

  • Washington University School of Medicine, St. Louis, MO

  • Children's Hospital Boston, Boston, MA

  • Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA

Locations

  • United States

  • Australia

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Neuroblastoma

Biomarkers

  • Hormone receptor

Drug/Treatment

  • Cyclophosphamide

  • Cyclophosphamide Injection

  • Carboplatin

  • Etoposide

  • Etoposide phosphate

  • Melphalan

  • Topotecan Hydrochloride

Outcome

  • N/A

Study Design

  • Randomized

Phase

  • III

Study Id's

  • NCT00567567

Sponsors

  • N/A

Result

  • Final

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