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e23279 : DNA repair defect and RAS mutation in Schistosoma mansoni-associated colorectal cancer patients: Carcinogenesis steps or mere coincidence?

Researchers

Presenter

  • Gustavo Fernandes Godoy Almeida

Principal Investigators

  • Luiz Alberto Reis Mattos

  • Joao Bosco Oliveira Filho

  • Paula Carvalho

  • Bruno Rolim de Brito

  • Estela Reis Alcantara

  • Caroline Teixeira Pinto

  • Filipe W Sarinho

  • Andre M Galvao

  • Mauricio Assuero Lima de Freitas

  • Igor M. L. Snitcovsky

  • Miriam H.H. Federico

Medical Centers

  • Hospital das Clinicas Federal University of Pernambuco, Recife, Brazil

  • Federal University of Pernambuco, Recife, Brazil

  • Federal University of Pernambuco, Recife, Brazil

  • ICESP Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil

  • Faculdade de Medicina USP, Cotia-sp, Brazil

Locations

  • Brazil

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Colorectal Cancer

  • DNA repair defect

  • Solid malignancies

Biomarkers

  • Mismatch repair endonuclease PMS2

  • MutL Homolog 1

  • MutS Homolog 6

  • MutS protein homolog 2

  • GTPase Nras

  • KRAS proto-oncogene, GTPase

  • Microsatellite instability

  • RAS mutation

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final

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