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e23248 : A Pilot Study of the Impact of a Single Dose of Zolendronic acid on Biomarkers in Breast Cancer.

Researchers

Presenter

  • May Thet Cho

Principal Investigators

  • Jun Gong

  • Shiuan Chen

  • Hua Yu

  • Louise Wong

  • Robin Smith

  • Laura Kruper

  • Joanne E. Mortimer

Medical Centers

  • Barnes Jewish Hospital, Saint Louis, MO

  • City of Hope National Medical Center, Duarte, CA

  • City of Hope, Duarte, CA

  • City of Hope, Beckman Research Institute, Duarte, CA

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Breast cancer

  • Solid malignancies

Biomarkers

  • Phosphatase and tensin homolog

  • Progesterone receptor

  • Epidermal growth factor receptor

  • Interferon-alpha

  • Interleukin 1

  • Interleukin 6

  • Matrix metallopeptidase 9

  • Matrix metalloproteinase 1

  • Matrix metalloproteinase 2

  • Signal transducer and activator of transcription 3

  • Tumor necrosis factor

  • Vascular endothelial growth factor A

Drug/Treatment

  • Zolendronic acid

  • DLP201

  • Mecasermin

  • IFN-lambda

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • NCT01409811

Sponsors

  • N/A

Result

  • Final

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