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e15006 : Relations between clinical outcomes and pharmacokinetics of irinotecan, oxaliplatin, and 5-fluorouracil during hepatic artery chronomodulated delivery of intravenous cetuximab in patients with extensive liver metastases from colorectal cancer: A translational study in European trial OPTILIV.

Researchers

Presenter

  • Francis Levi

Principal Investigators

  • Abdoulaye Karabou A

  • Marie-Christine Etienne-Grimaldi

  • Gilles Paintaud

  • C. N. J. Focan

  • Pasquale F. Innominato

  • Mohamed Bouchahda

  • Gerard Milano

  • Etienne Chatelut

Medical Centers

  • Hopital Paul Brousse, Villejuif, France

  • AK-SCIENCE, Vitry Sur Seine, France

  • Antoine Lacassagne Center, Nice, France

  • Universite Francois-Rabelais de Tours, CNRS, GICC UMR 7292, CHRU de Tours, Service de Pharmacologie-Toxicologie, Tours, France

  • Department of Oncology, Centre Hospitalier Chretien, Clinique Saint-Joseph, Liege, Belgium

  • Warwick Medical School, Coventry, United Kingdom

  • Medical Oncology Department, INSERM U935, Paul Brousse Hospital, Villejuif, France

  • Laboratory of Oncopharmacology, Antoine Lacassagne Center, Nice, France

  • Institut Claudius Regaud, IUCT, equipe n14, Universite Paul Sabatier, Toulouse, France

Locations

  • France

  • United Kingdom

  • Belgium

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Colorectal Cancer

  • Secondary liver cancer

  • Solid malignancies

Biomarkers

  • N/A

Drug/Treatment

  • Adrucil injection

  • Oxaliplatin

  • Irinotecan

  • Erbitux

Outcome

  • N/A

Study Design

  • Pharmacokinetics

Phase

  • NA

Study Id's

  • NCT00852228

Sponsors

  • N/A

Result

  • Final

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