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11517 : Epidermal growth factor receptor mRNA expression in circulating tumor cells as a potential mechanism of molecular escape from regorafenib therapy.

Researchers

Presenter

  • Satoshi Matsusaka

Principal Investigators

  • Yan Ning

  • Dongyun Yang

  • Wu Zhang

  • Diana L. Hanna

  • Shu Cao

  • Mitsukuni Suenaga

  • Satoshi Okazaki

  • Martin D. Berger

  • Heinz-Josef Lenz

Medical Centers

  • Department of Pharmacy,The Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan

  • University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA

  • USC Norris Comprehensive Cancer Center, Los Angeles, CA

  • Division of Medical Oncology, USC Norris Comprehensive Cancer Center, Los Angeles, CA

  • University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA

  • Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Los Angeles, CA

  • University of Southern California, Los Angeles, CA

Locations

  • United States

  • Japan

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Gastroenterology (GU)

Disease

  • Colorectal Cancer

Biomarkers

  • Carcinoembryonic antigen

  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

  • Circulating tumor cells

  • Epidermal growth factor

  • Epidermal growth factor receptor

  • Epithelial Cell Adhesion Molecule

  • Solute Carrier Family 22 Member 3

  • Twist-related protein 1

Drug/Treatment

  • Regorafenib

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final

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