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575 : A retrospective study of SPAG5 expression and its clinical implications in >8,000 patients of ER positive (ER+) breast cancer (BC): Genomic, transcriptomic and protein analysis.

Researchers

Presenter

  • Tarek M. A. Abdel-Fatah

Principal Investigators

  • Devika Agarwal

  • Dong-Xu Liu

  • Roslin Russell

  • Oscar M Rueda

  • Lorinc Pongor

  • Balazs Gyorffy

  • Paul M Moseley

  • Andrew Green

  • A Graham Pockley

  • Robert Rees

  • Carlos Caldas

  • Ian O. Ellis

  • Graham Ball

  • Stephen Chan

Medical Centers

  • Nottingham University City Hospital NHS Trust, Nottingham, United Kingdom

  • Nottingham Trent University - The John van Geest Cancer Research Centre, Nottingham, United Kingdom

  • The University of Auckland - Liggins Institute, Auckland, New Zealand

  • Cancer Research UK, Cambridge Research Institute, Cambridge, United Kingdom

  • Semmelweis University, Budapest, Hungary

  • University of Nottingham, Nottingham, United Kingdom

  • John van Geest Cancer Research Centre, School of Science and Technology, Nottingham Trent University, Clifton Campus, Nottingham, United Kingdom

  • John van Geest Cancer Research Centre, School of Science and Technology, Nottingham Trent University, Clifton Campus, Nottingham, United Kingdom

  • Department of Oncology, University of Cambridge, Cambridge, United Kingdom

  • Division of Pathology, Nottingham University Hospitals, Nottingham, United Kingdom

  • Nottingham University City Hospital NHS Trust, Nottingham, United Kingdom

Locations

  • United Kingdom

  • New Zealand

  • Hungary

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Breast cancer

Biomarkers

  • BRCA mutation

  • Sperm Associated Antigen 5

Drug/Treatment

  • Tamoxifen

Outcome

  • N/A

Study Design

  • Multinational

  • Cohort

Phase

  • II

Study Id's

  • NCT00455533

Sponsors

  • N/A

Result

  • Final

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